Parkinson’s disease is a neurodegenerative process of the extrapyramidal system which affects approximately 1% of individuals older than 50 years of age. The English physician, James Parkinson, first described the disease in 1817. The most important clinical manifestations are resting tremor, rigidity, slowness of movement (bradykinesia), postural instability and masklike facial expression. The causes of Parkinson’s disease are not entirely known. Some cases may have a familial component. Rarely, the disease is associated with viral neurotrophic infections or toxins such as manganese or derivatives of heroin.
En algunos casos puede tener componente familiar y en raras ocasiones se asocia a infecciones neurotrópicas virales o a tóxicos como el manganeso o derivados de la heroína.